Staff Scientist II, CryoEM

Working at Yale means contributing to a better tomorrow. Whether you are a current resident of our New Haven-based community- eligible for opportunities through the New Haven Hiring Initiative or a newcomer, interested in exploring all that Yale has to offer, your talents and contributions are welcome. Discover your opportunities at Yale! Salary Range $68,000.00 - $120,500.00 Job Requisition ID 132803WD Position Focus: The Yale CryoEM Resource (YCR) is a university-wide cryo-electron microscopy facility with three sites across Yale’s campuses: Science Hill, the Yale School of Medicine, and West Campus. YCR houses a comprehensive suite of transmission electron microscopes supporting a wide range of applications, including TEM characterization, single-particle analysis, cryo-electron tomography, and microcrystal electron diffraction. The facility also includes significant expansion space with unoccupied EM rooms intended for future instruments, offering strong capacity for growth and collaboration. As a multi-user facility, YCR works closely with users at Yale as well as with external academic and industry users. We invite applications for a CryoEM Specialist to join the YCR team. Reporting to the YCR Managing Director, the specialist will work with users across Yale and with external academic and industry users. The position is primarily based at the Science Hill site, with activities at the Yale School of Medicine and West Campus as needed. Key responsibilities include user training, cryoEM service delivery, guidance in experimental design, sample preparation, data collection, and image analysis, as well as contributing to reliable instrument operation, service coordination, and safety compliance across the YCR. Required Skills and Abilities 1.Demonstrated expertise in cryoEM, including experimental design, sample preparation, screening, data collection, data analysis, and scientific troubleshooting. 2.Demonstrated ability to collaborate and work effectively with scientists from a wide range of backgrounds. 3.Excellent written and verbal communication abilities. 4.Project management: strong organizational and project management skills to support facility operations. 5.Technical knowledge: in-depth understanding of relevant research techniques and methodologies. Preferred Education, Experience and Skills Ph.D. or equivalent in biology, chemistry, physics, biophysics, structural biology or a closely related field. Principal Responsibilities 1. User Training: Provide advanced training and guidance to users of the research core. 2. Experiment Support: Collaborate with researchers on experimental design, execution, data analysis, and troubleshooting within the research core. 3. Facility/Instrument Support: Manage and oversee research projects within the research core. 4. Technique Development: Lead the implementation and optimization of advanced techniques and methodologies and develop standard operating procedures for research core services. 5. Data Analysis/Interpretation: Analyze and interpret complex scientific data, generating meaningful insights and recommendations. 6. Equipment Procurement: Assist in the selection, acquisition, and maintenance of research core equipment. 7. Professional Development: Stay updated with emerging research trends and technologies. Participate in professional development activities and scientific conferences. 8. Scientific Participation: Contribute scientific data for manuscript preparation and grant proposals 9. Staff Training and Mentoring: Contribute to the training and mentoring of junior staff members. 10. Vendor Relations: Manage vendor relationships, negotiates contracts, and evaluates new technologies for optimal procurement processes. 11. Education and Outreach: Contribute to education and outreach activities within the core, including tours, events, etc. Required Education and Experience Bachelor’s degree in a related discipline and four years of related experience or an equivalent combination of skills, education, and experience. Original Job Posting Date 03/03/2026 Job Category Professional Bargaining Unit NON Compensation Grade Administration & Operations Compensation Grade Profile Supervisor; Senior Associate (24) Time Type Full time Duration Type Staff Work Model On-site Location 260 Whitney Avenue, New Haven, Connecticut Background Check Requirements All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. For additional information on the background check requirements and process visit "Learn about background checks" under the Applicant Support Resources section of Careers on the It's Your Yale website. Health Requirements Certain positions have associated health requirements based on specific job responsibilities. These may include vaccinations, tests, or examinations, as required by law, regulation, or university policy. Posting Disclaimer The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties  and responsibilities of the position. Employees will be assigned specific job-related duties through  their hiring department. University policy is committed to affirmative action under law in employment of women, minority group members, individuals with disabilities, and protected veterans. Additionally, in accordance with Yale's Policy Against Discrimination and Harassment, and as delineated by federal and Connecticut law, Yale does not discriminate in admissions, educational programs, or employment against any individual on account of that individual's sex, sexual orientation, gender identity or expression, race, color, national or ethnic origin, religion, age, disability, status as a special disabled veteran, veteran of the Vietnam era or other covered veteran. Inquiries concerning Yale's Policy Against Discrimination and Harassment may be referred to the Office of Institutional Equity and Accessibility (OIEA). Note Yale University is a tobacco-free campus.