Computational Protein Engineer

<div> <p class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">Our client is a prominent biotech organization advancing groundbreaking antibody and protein design initiatives.</span></p> <p class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif"> </span></p> <p class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">They are in need of a <strong>Lead Scientist, Protein Design to oversee experimental projects while utilizing computational methods </strong>to expedite and enhance design processes.</span></p> <p class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif"> </span></p> <p class="MsoNormal"><strong><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">The perfect candidate will be responsible for the following:</span></strong></p> <p class="MsoNormal"><strong><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif"> </span></strong></p> <ul> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif"><strong>Direct experimental planning and implementation of antibody and protein design initiatives</strong> such as enhancing affinity, developing multi-specific antibodies, and creating new binders from scratch</span></li> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">Lead protein production, purification, and assessment processes across various platforms</span></li> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif"><strong>Create and conduct binding and functional tests</strong> to assess and refine engineered proteins</span></li> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">Collaborate with structural experts and computational researchers to incorporate structural findings into experimental projects</span></li> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">Utilize computational tools like AlphaFold and Rosetta to aid and inform wet lab approaches</span></li> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">Oversee CRO collaborations including planning experiments, communicating with vendors, and internal documentation</span></li> </ul> <p class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif"> </span></p> <p class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif"> </span></p> <p class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif"> </span></p> <p class="MsoNormal"><strong><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">The ideal candidate will meet the following qualifications:</span></strong></p> <p class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif"> </span></p> <ul> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">PhD in biochemistry, molecular biology, protein chemistry, or related field with at least 2 years of industry experience</span></li> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">Hands-on knowledge in protein production, purification, and evaluation</span></li> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">Experience with antibody design technologies like bispecifics, nanobodies, or similar formats</span></li> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">Published work and/or patents related to antibody or protein design</span></li> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">Familiarity with design tools (AlphaFold, Rosetta, ProteinMPNN) would be advantageous</span></li> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">Proven ability to lead technical teams and oversee complex, multi-dimensional projects</span></li> <li class="MsoNormal"><span style="font-size: 12pt;line-height: 115%;font-family: tahoma, arial, helvetica, sans-serif">Excellent written and verbal communication abilities</span></li> </ul> </div>