Postdoc Position in Epigenome Engineering

Postdoc Position in Epigenome Engineering

• Faculty:
• Faculty of Science
• Department:
• Department of Biology
• Hours per week:
• 36 to 40
• Application deadline:

Chemical modifications of histones and DNA provide an important regulatory layer for gene expression control and numerous other processes in the cell. In this context, individual and combinatorial modifications guide spatiotemporal recruitment of regulatory factors to specific regions in the genome. Despite many efforts to characterise chromatin-mediated regulation of gene activity, the direct involvement of chromatin marks in instructing transcriptional outcomes remains unclear and requires further investigation.

Your job

This project aims to bridge chromatin engineering and epigenomics to study epigenetic regulation of transcriptional processes. Potential approaches will involve manipulation of epigenetic marks in embryonic stem cells, investigating changes in epigenetic landscapes and transcription upon controlled manipulation, and/or engineering of synthetic chromatin states. You are encouraged to bring in your individual ideas and expertise to the current project and furthermore to develop new project ideas.

Your qualities

You are dedicated scientist with a background in chromatin biology and/or gene regulation and experience in cell engineering, molecular cloning, genomics, and computational data analysis workflows. In addition you:

• have obtained, or are on track to obtain, a PhD with first or co-author publications/preprints in the respective field;
• you are able to work independently as well as collaboratively in a team;
• demonstrate strong written and oral communication skills in English.

Our offer

• an independent postdoc position for initially one year (1.0 FTE), with an extension of two years upon a positive evaluation;
• a gross monthly salary, depending on experience and qualifications, between € 3.546 and €5.538 in the case of full-time employment (salary scale 10 under the Collective Labour Agreement for Dutch Universities (CAO NU));
• 8% holiday pay and 8.3% year-end bonus;
• a pension scheme, partially paid parental leave and flexible terms of employment based on the CAO NU.

In addition to the terms of employment laid down in the CAO NU, Utrecht University also offers a range of its own schemes for employees. This includes arrangements for professional development, various types of leave, and options for sports and cultural activities. You can also tailor your employment conditions through our Terms of Employment Options Model. In this way, we encourage you to keep investing in your personal and professional development. For more information, please visit Working at Utrecht University.

About us

A better future for everyone. This ambition motivates our scientists in executing their leading research and inspiring teaching. At Utrecht University, the various disciplines collaborate intensively towards major strategic themes. Our focus is on Dynamics of Youth, Institutions for Open Societies, Life Sciences and Pathways to Sustainability. Sharing science, shaping tomorrow.

Working at the Faculty of Science

The Genome Biology & Epigenetics (GBE)

The Baubec lab

More information

For more information, please contact Tuncay Baubec

Do you have a question about the application procedure? Please send an email to science.recruitment@uu.nl.
 

Apply now

As Utrecht University, we want to be a home for everyone. We value staff with diverse backgrounds, perspectives and identities, including cultural, religious or ethnic background, gender, sexual orientation, disability or age. We strive to create a safe and inclusive environment in which everyone can flourish and contribute.
A knowledge security screening can be part of the selection procedures of academic staff. We do this, among other things, to prevent the unwanted transfer of sensitive knowledge and technology.
If you are enthusiastic about this position, just apply via the "Apply now" button! Please enclose:

• your letter of motivation;
• your Curriculum vitae;
• the names, telephone numbers, and email addresses of at least two references.

If this specific opportunity isn’t for you, but you know someone else who may be interested, please forward this vacancy to them.

Some connections are fundamental – Be one of them
#FundamentalConnection

The application deadline is 31 August 2026.